Cargando…

Overexpression of CD59 inhibits apoptosis of T-acute lymphoblastic leukemia via AKT/Notch1 signaling pathway

BACKGROUND: T-acute lymphoblastic leukemia (T-ALL) was a hematological malignancy characterized by the accumulation of immature T cells in bone marrow and peripheral blood. In this study, we tried to explore the physiological role of CD59 in T-ALL. METHODS: In this study, we collected the bone marro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Yanfei, Qi, Yan, Wang, Yunshan, Ma, Xiaoli, Xu, Yihui, Wang, Jun, Zhang, Xiaoqian, Gao, Meihua, Cong, Beibei, Han, Shuyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325688/ https://www.ncbi.nlm.nih.gov/pubmed/30636930 http://dx.doi.org/10.1186/s12935-018-0714-9

Ejemplares similares

Mutations increased overexpression of Notch1 in T-cell acute lymphoblastic leukemia
por: Lin, Chunlan, et al.
Publicado: (2012)

lncRNA DLEU2 promotes gastric cancer progression through ETS2 via targeting miR-30a-5p
por: Han, Shuyi, et al.
Publicado: (2021)

Overexpression of MALT1-A20-NF-κB in adult B-cell acute lymphoblastic leukemia
por: Xu, Yi, et al.
Publicado: (2015)

Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia
por: Shi, Ce, et al.
Publicado: (2020)

Analysis of the expression of PHTF1 and related genes in acute lymphoblastic leukemia
por: Huang, Xin, et al.
Publicado: (2015)

Haploinsufficiency of NR3C1 drives glucocorticoid resistance in adult acute lymphoblastic leukemia cells by down-regulating the mitochondrial apoptosis axis, and is sensitive to Bcl-2 blockage
por: Xiao, Haowen, et al.
Publicado: (2019)

An improved advanced fragment analysis-based classification and risk stratification of pediatric acute lymphoblastic leukemia
por: Sun, Yanran, et al.
Publicado: (2019)

BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes
por: Wu, Shuiyan, et al.
Publicado: (2021)

WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia
por: Luo, Hao, et al.
Publicado: (2019)

The prognostic potential of coilin in association with p27 expression in pediatric acute lymphoblastic leukemia for disease relapse
por: Yue, Zhi-Xia, et al.
Publicado: (2018)

An age-based, RNA expression paradigm for survival biomarker identification for pediatric neuroblastoma and acute lymphoblastic leukemia
por: Diviney, Andrea, et al.
Publicado: (2019)

Mst1 overexpression combined with Yap knockdown augments thyroid carcinoma apoptosis via promoting MIEF1-related mitochondrial fission and activating the JNK pathway
por: Zhang, Xiaoli, et al.
Publicado: (2019)

FPGS rs1544105 polymorphism is associated with treatment outcome in pediatric B-cell precursor acute lymphoblastic leukemia
por: Liu, Shu-Guang, et al.
Publicado: (2013)

Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt’s B cell lymphoma
por: Townsend, Michelle H., et al.
Publicado: (2020)

Targeting Akt by SC66 triggers GSK-3β mediated apoptosis in colon cancer therapy
por: Liu, Yeying, et al.
Publicado: (2019)

Effect of nicastrin on hepatocellular carcinoma proliferation and apoptosis through PI3K/AKT signalling pathway modulation
por: Wang, Xicheng, et al.
Publicado: (2020)

Deguelin induces the apoptosis of lung cancer cells through regulating a ROS driven Akt pathway
por: Xu, Huae, et al.
Publicado: (2015)

Transcription factor E2F3a regulates CASP8AP2 transcription and enhances sensitivity to chemotherapeutic drugs in acute lymphoblastic leukemia
por: Liu, Fei-Fei, et al.
Publicado: (2018)

MiR-133b regulates bladder cancer cell proliferation and apoptosis by targeting Bcl-w and Akt1
por: Chen, Xiao-nan, et al.
Publicado: (2014)

Protopine triggers apoptosis via the intrinsic pathway and regulation of ROS/PI3K/Akt signalling pathway in liver carcinoma
por: Nie, Chunhui, et al.
Publicado: (2021)

LncRNA ANRIL/miR-7-5p/TCF4 axis contributes to the progression of T cell acute lymphoblastic leukemia
por: Li, Gang, et al.
Publicado: (2020)

Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis
por: Xu, Peng, et al.
Publicado: (2022)

Inhibition of the AKT pathway in cholangiocarcinoma by MK2206 reduces cellular viability via induction of apoptosis
por: Wilson, Jacob M, et al.
Publicado: (2015)

The antiproliferative effect of C(2)-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFκB
por: Lin, I-Ling, et al.
Publicado: (2014)

Establishment and characterization of a novel childhood acute lymphoblastic leukemia cell line, HXEX-ALL1, with chromosome 9p and 17p deletions
por: Zhu, Yiping, et al.
Publicado: (2019)

Association of relapse-linked ARID5B single nucleotide polymorphisms with drug resistance in B-cell precursor acute lymphoblastic leukemia cell lines
por: Tamai, Minori, et al.
Publicado: (2020)

Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression
por: Tsaouli, Georgia, et al.
Publicado: (2019)

Serum apolipoprotein E concentration and polymorphism influence serum lipid levels in Chinese Shandong Han population
por: Han, ShuYi, et al.
Publicado: (2016)

Notch1 signaling is involved in regulating Foxp3 expression in T-ALL
por: Luo, Xiaodan, et al.
Publicado: (2013)

Down regulation of G protein-coupled receptor 137 expression inhibits proliferation and promotes apoptosis in leukemia cells
por: Men, Li-Jie, et al.
Publicado: (2018)

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia
por: Choi, Sung Hee, et al.
Publicado: (2017)

Nicotine Inhibits Cisplatin-Induced Apoptosis via Regulating α5-nAChR/AKT Signaling in Human Gastric Cancer Cells
por: Jia, Yanfei, et al.
Publicado: (2016)

A novel prognostic model based on single-cell RNA sequencing data for hepatocellular carcinoma
por: Lu, Juan, et al.
Publicado: (2022)

N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity
por: Keenan, Bryce, et al.
Publicado: (2020)

Characterization of a novel glucocorticoid-resistant human B-cell acute lymphoblastic leukemia cell line, with AMPK, mTOR and fatty acid synthesis pathway inhibition
por: Li, Yuanyuan, et al.
Publicado: (2021)

BAD overexpression inhibits cell growth and induces apoptosis via mitochondrial-dependent pathway in non-small cell lung cancer
por: Jiang, Li, et al.
Publicado: (2013)

CDA gene silencing regulated the proliferation and apoptosis of chronic myeloid leukemia K562 cells
por: Wei, Xiao-Fang, et al.
Publicado: (2018)

Tanshinone IIA regulates human AML cell proliferation, cell cycle, and apoptosis through miR-497-5p/AKT3 axis
por: Nie, Zi-Yuan, et al.
Publicado: (2020)

LINC01806 mediated by STAT1 promotes cell proliferation, migration, invasion, and stemness in non-small cell lung cancer through Notch signaling by miR-4428/NOTCH2 axis
por: Huang, Shangxiao, et al.
Publicado: (2022)

DEC1 promotes progression of Helicobacter pylori‐positive gastric cancer by regulating Akt/NF‐κB pathway
por: Jia, Yanfei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1i25r622ucskg4c0coomgv6ht6