Novel linear lipopeptide paenipeptin C′ binds to lipopolysaccharides and lipoteichoic acid and exerts bactericidal activity by the disruption of cytoplasmic membrane

BACKGROUND: There is an urgent need to develop potent antimicrobials for the treatment of infections caused by antibiotic-resistant bacterial pathogens. Paenipeptin C′ (C8-Pat) is a novel linear lipopeptide recently discovered by our group. The objectives of this study were to determine the time-kil...

Descripción completa

Detalles Bibliográficos
Autores principales: Moon, Sun Hee, Huang, En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325689/
https://www.ncbi.nlm.nih.gov/pubmed/30621590
http://dx.doi.org/10.1186/s12866-018-1381-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325689/
https://www.ncbi.nlm.nih.gov/pubmed/30621590
http://dx.doi.org/10.1186/s12866-018-1381-7

Ejemplares similares