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The X chromosome and sex-specific effects in infectious disease susceptibility

The X chromosome and X-linked variants have largely been ignored in genome-wide and candidate association studies of infectious diseases due to the complexity of statistical analysis of the X chromosome. This exclusion is significant, since the X chromosome contains a high density of immune-related...

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Detalles Bibliográficos
Autores principales: Schurz, Haiko, Salie, Muneeb, Tromp, Gerard, Hoal, Eileen G., Kinnear, Craig J., Möller, Marlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325731/
https://www.ncbi.nlm.nih.gov/pubmed/30621780
http://dx.doi.org/10.1186/s40246-018-0185-z