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Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma

BACKGROUND: Xanthoangelol (XAG) was reported to exhibit antitumor properties in several cancer. However, the specific anti-tumor activity of XAG in human hepatocellular carcinoma (HCC) and the relevant mechanisms are not known. METHODS: The effects of XAG on HCC cell proliferation and apoptosis were...

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Detalles Bibliográficos
Autores principales: Li, Zichao, Zhang, Luying, Gao, Mingquan, Han, Mei, Liu, Kaili, Zhang, Zhuang, Gong, Zhi, Xing, Lifei, Shi, Xianzhou, Lu, Kui, Gao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325734/
https://www.ncbi.nlm.nih.gov/pubmed/30621754
http://dx.doi.org/10.1186/s13046-018-1012-z