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Early treatment with minocycline following stroke in rats improves functional recovery and differentially modifies responses of peri-infarct microglia and astrocytes

BACKGROUND: Altered neuronal connectivity in peri-infarct tissue is an important contributor to both the spontaneous recovery of neurological function that commonly develops after stroke and improvements in recovery that have been induced by experimental treatments in animal models. Microglia and as...

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Detalles Bibliográficos
Autores principales: Yew, Wai Ping, Djukic, Natalia D., Jayaseelan, Jaya S. P., Walker, Frederick R., Roos, Karl A. A., Chataway, Timothy K., Muyderman, Hakan, Sims, Neil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325745/
https://www.ncbi.nlm.nih.gov/pubmed/30626393
http://dx.doi.org/10.1186/s12974-018-1379-y