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Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis

OBJECTIVE: The goal of this study was to explore the role of bradykinins and bradykinin 1 receptor (B1R) in murine lupus nephritis. METHODS: C57BL/6 and MRL/lpr mice were compared for renal expression of B1R and B2R by western blot and immunohistochemistry. MRL/lpr lupus-prone mice were administered...

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Detalles Bibliográficos
Autores principales: Qin, Ling, Du, Yong, Ding, Huihua, Haque, Anam, Hicks, John, Pedroza, Claudia, Mohan, Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325757/
https://www.ncbi.nlm.nih.gov/pubmed/30621761
http://dx.doi.org/10.1186/s13075-018-1774-x