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Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis
OBJECTIVE: The goal of this study was to explore the role of bradykinins and bradykinin 1 receptor (B1R) in murine lupus nephritis. METHODS: C57BL/6 and MRL/lpr mice were compared for renal expression of B1R and B2R by western blot and immunohistochemistry. MRL/lpr lupus-prone mice were administered...
Autores principales: | Qin, Ling, Du, Yong, Ding, Huihua, Haque, Anam, Hicks, John, Pedroza, Claudia, Mohan, Chandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325757/ https://www.ncbi.nlm.nih.gov/pubmed/30621761 http://dx.doi.org/10.1186/s13075-018-1774-x |
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