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Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction
BACKGROUND: In heart failure the myocardium becomes insulin resistant which negatively influences cardiac energy metabolism and function, while increasing cardiac insulin signalling improves cardiac function and prevents adverse remodelling in the failing heart. Glucagon’s action on cardiac glucose...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325856/ https://www.ncbi.nlm.nih.gov/pubmed/30626440 http://dx.doi.org/10.1186/s12933-019-0806-4 |