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CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans
The Caenorhabditis elegans Gene Knockout Consortium is tasked with obtaining null mutations in each of the more than 20,000 open reading frames (ORFs) of this organism. To date, approximately 15,000 ORFs have associated putative null alleles. As there has been substantial success in using CRISPR/Cas...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325907/ https://www.ncbi.nlm.nih.gov/pubmed/30420468 http://dx.doi.org/10.1534/g3.118.200778 |