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FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer

PURPOSE: Therapy response to neoadjuvant radiochemotherapy (nRCT) of locally advanced rectal cancer varies widely so that markers predicting response are urgently needed. Fibroblast growth factor (FGF) and FGF receptor (FGFR) signaling is involved in pro-survival signaling and thereby may result in...

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Detalles Bibliográficos
Autores principales: Harpain, Felix, Ahmed, Mohamed A., Hudec, Xenia, Timelthaler, Gerald, Jomrich, Gerd, Müllauer, Leonhard, Selzer, Edgar, Dörr, Wolfgang, Bergmann, Michael, Holzmann, Klaus, Grasl-Kraupp, Bettina, Grusch, Michael, Berger, Walter, Marian, Brigitte, Silberhumer, Gerd R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326005/
https://www.ncbi.nlm.nih.gov/pubmed/30276721
http://dx.doi.org/10.1007/s00432-018-2757-7