Cargando…

FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer

PURPOSE: Therapy response to neoadjuvant radiochemotherapy (nRCT) of locally advanced rectal cancer varies widely so that markers predicting response are urgently needed. Fibroblast growth factor (FGF) and FGF receptor (FGFR) signaling is involved in pro-survival signaling and thereby may result in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harpain, Felix, Ahmed, Mohamed A., Hudec, Xenia, Timelthaler, Gerald, Jomrich, Gerd, Müllauer, Leonhard, Selzer, Edgar, Dörr, Wolfgang, Bergmann, Michael, Holzmann, Klaus, Grasl-Kraupp, Bettina, Grusch, Michael, Berger, Walter, Marian, Brigitte, Silberhumer, Gerd R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Article – Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326005/ https://www.ncbi.nlm.nih.gov/pubmed/30276721 http://dx.doi.org/10.1007/s00432-018-2757-7

Ejemplares similares

Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer
por: Ahmed, Mohamed A., et al.
Publicado: (2016)

Correction: Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer
por: Ahmed, Mohamed A., et al.
Publicado: (2019)

Expression of FGF8, FGF18, and FGFR4 in Gastroesophageal Adenocarcinomas
por: Jomrich, Gerd, et al.
Publicado: (2019)

Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis()()
por: Erdem, Zeynep N., et al.
Publicado: (2017)

Programmed death-ligand 1 expression in rectal cancer
por: Jomrich, G., et al.
Publicado: (2016)

Interaction of FGF9 with FGFR3‐IIIb/IIIc, a putative driver of growth and aggressive behaviour of hepatocellular carcinoma
por: Paur, Jakob, et al.
Publicado: (2020)

FGF5 is expressed in melanoma and enhances malignancy in vitro and in vivo
por: Ghassemi, Sara, et al.
Publicado: (2017)

A siphon-like retrogastric transverse colon: A case report
por: Harpain, Felix, et al.
Publicado: (2018)

Circulating FGF18 is decreased in pleural mesothelioma but not correlated with disease prognosis
por: Mosleh, Berta, et al.
Publicado: (2023)

Inhibin/activin expression in human and rodent liver: subunits α and βB as new players in human hepatocellular carcinoma?
por: Frost, K, et al.
Publicado: (2011)

Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration
por: Sonvilla, G, et al.
Publicado: (2010)

Comparison of Inflammation-Based Prognostic Scores in a Cohort of Patients with Resectable Esophageal Cancer
por: Jomrich, G., et al.
Publicado: (2017)

The modified glasgow prognostic score is an independent prognostic indicator in neoadjuvantly treated adenocarcinoma of the esophagogastric junction
por: Jomrich, Gerd, et al.
Publicado: (2018)

Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications
por: Schiffmann, Leif, et al.
Publicado: (2013)

Preoperative BChE serves as a prognostic marker in patients with resectable AEG after neoadjuvant chemotherapy
por: Gensthaler, Lisa, et al.
Publicado: (2023)

Neoadjuvant radiotherapy for rectal cancer management
por: Feeney, Gerard, et al.
Publicado: (2019)

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression
por: Englinger, Bernhard, et al.
Publicado: (2016)

Sarcopenia and sarcopenic obesity are independent adverse prognostic factors in resectable pancreatic ductal adenocarcinoma
por: Gruber, Elisabeth S., et al.
Publicado: (2019)

The Prognostic Index Independently Predicts Survival in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Resection
por: Gruber, Elisabeth S., et al.
Publicado: (2020)

Correction: Sarcopenia and sarcopenic obesity are independent adverse prognostic factors in resectable pancreatic ductal adenocarcinoma
por: Gruber, Elisabeth S., et al.
Publicado: (2020)

Phenobarbital Induces Alterations in the Proteome of Hepatocytes and Mesenchymal Cells of Rat Livers
por: Klepeisz, Philip, et al.
Publicado: (2013)

Next generation sequencing: clinical applications in solid tumours
por: Müllauer, Leonhard
Publicado: (2017)

Milestones in pathology—from histology to molecular biology
por: Müllauer, Leonhard
Publicado: (2017)

Molecular Pathology of Cancer: The Past, the Present, and the Future
por: Müllauer, Leonhard
Publicado: (2021)

Radiotherapy as a Backbone for Novel Concepts in Cancer Immunotherapy
por: Kabiljo, Julijan, et al.
Publicado: (2019)

Multimodality locoregional treatment strategies for bridging HCC patients before liver transplantation
por: Györi, Georg P., et al.
Publicado: (2017)

Assessment of response to neoadjuvant radiochemotherapy with F-18 FLT and F-18 FDG PET/CT in patients with rectal cancer
por: Rendl, Gundula, et al.
Publicado: (2014)

Systemic Immune-Inflammation Index (SII) Predicts Poor Survival in Pancreatic Cancer Patients Undergoing Resection
por: Jomrich, Gerd, et al.
Publicado: (2019)

MELD-Na Alterations on the Liver Transplant Waiting List and Their Impact on Listing Outcome
por: Silberhumer, Gerd R., et al.
Publicado: (2023)

VARIFI—Web-Based Automatic Variant Identification, Filtering and Annotation of Amplicon Sequencing Data
por: Krunic, Milica, et al.
Publicado: (2019)

Prognosis of rectal cancer patients improves with downstaging by intensified neoadjuvant radiochemotherapy - a matched pair analysis
por: Schiffmann, Leif, et al.
Publicado: (2013)

Genomic alterations in thymoma—molecular pathogenesis?
por: Oberndorfer, Felicitas, et al.
Publicado: (2020)

Neoadjuvant Treatment in Rectal Cancer: Actual Status
por: Garajová, Ingrid, et al.
Publicado: (2011)

Neoadjuvant Chemotherapy in Locally Advanced Rectal Cancer
por: Papaccio, Federica, et al.
Publicado: (2020)

Restaging rectal cancer following neoadjuvant chemoradiotherapy
por: Cuicchi, Dajana, et al.
Publicado: (2023)

Expression of FGFR1–4 in Malignant Pleural Mesothelioma Tissue and Corresponding Cell Lines and its Relationship to Patient Survival and FGFR Inhibitor Sensitivity
por: Vlacic, Gregor, et al.
Publicado: (2019)

Sphinkeeper Procedure for Treating Severe Faecal Incontinence—A Prospective Cohort Study
por: Dawoud, Christopher, et al.
Publicado: (2021)

Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies
por: Jo, Peter, et al.
Publicado: (2016)

Systemic mastocytosis associated with chronic myelomonocytic leukemia and xanthogranuloma
por: Tschandl, Philipp, et al.
Publicado: (2012)

Meta-analysis of neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for locally advanced rectal cancer
por: Lin, Huaqin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_29l5u92ililcq34goosicdlbhl