PARP inhibitors affect growth, survival and radiation susceptibility of human alveolar and embryonal rhabdomyosarcoma cell lines

PURPOSE: PARP inhibitors (PARPi) are used in a wide range of human solid tumours but a limited evidence is reported in rhabdomyosarcoma (RMS), the most frequent childhood soft-tissue sarcoma. The cellular and molecular effects of Olaparib, a specific PARP1/2 inhibitor, and AZD2461, a newly synthesiz...

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Detalles Bibliográficos
Autores principales: Camero, Simona, Ceccarelli, Simona, De Felice, Francesca, Marampon, Francesco, Mannarino, Olga, Camicia, Lucrezia, Vescarelli, Enrica, Pontecorvi, Paola, Pizer, Barry, Shukla, Rajeev, Schiavetti, Amalia, Mollace, Maria Giovanna, Pizzuti, Antonio, Tombolini, Vincenzo, Marchese, Cinzia, Megiorni, Francesca, Dominici, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326011/
https://www.ncbi.nlm.nih.gov/pubmed/30357520
http://dx.doi.org/10.1007/s00432-018-2774-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326011/
https://www.ncbi.nlm.nih.gov/pubmed/30357520
http://dx.doi.org/10.1007/s00432-018-2774-6

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