Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children

OBJECTIVES: The objectives of this study were to investigate the population pharmacokinetics of posaconazole in immunocompromised children, evaluate the influence of patient characteristics on posaconazole exposure and perform simulations to recommend optimal starting doses. METHODS: Posaconazole pl...

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Detalles Bibliográficos
Autores principales: Boonsathorn, Sophida, Cheng, Iek, Kloprogge, Frank, Alonso, Carlos, Lee, Charmion, Doncheva, Bilyana, Booth, John, Chiesa, Robert, Irwin, Adam, Standing, Joseph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326087/
https://www.ncbi.nlm.nih.gov/pubmed/29679234
http://dx.doi.org/10.1007/s40262-018-0658-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326087/
https://www.ncbi.nlm.nih.gov/pubmed/29679234
http://dx.doi.org/10.1007/s40262-018-0658-1

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