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Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children
OBJECTIVES: The objectives of this study were to investigate the population pharmacokinetics of posaconazole in immunocompromised children, evaluate the influence of patient characteristics on posaconazole exposure and perform simulations to recommend optimal starting doses. METHODS: Posaconazole pl...
Autores principales: | Boonsathorn, Sophida, Cheng, Iek, Kloprogge, Frank, Alonso, Carlos, Lee, Charmion, Doncheva, Bilyana, Booth, John, Chiesa, Robert, Irwin, Adam, Standing, Joseph F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326087/ https://www.ncbi.nlm.nih.gov/pubmed/29679234 http://dx.doi.org/10.1007/s40262-018-0658-1 |
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