Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP(3)-Evoked Ca(2+) Signals through Sigma-1 Receptors

Sigma-1 receptors (Sig-1Rs) are integral ER membrane proteins. They bind diverse ligands, including psychoactive drugs, and regulate many signaling proteins, including the inositol 1,4,5-trisphosphate receptors (IP(3)Rs) that release Ca(2+) from the ER. The endogenous ligands of Sig-1Rs are unknown....

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Detalles Bibliográficos
Autores principales: Brailoiu, Eugen, Chakraborty, Sumita, Brailoiu, G. Cristina, Zhao, Pingwei, Barr, Jeffrey L., Ilies, Marc A., Unterwald, Ellen M., Abood, Mary E., Taylor, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326163/
https://www.ncbi.nlm.nih.gov/pubmed/30625315
http://dx.doi.org/10.1016/j.celrep.2018.12.051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326163/
https://www.ncbi.nlm.nih.gov/pubmed/30625315
http://dx.doi.org/10.1016/j.celrep.2018.12.051

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