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Mouse embryonic stem cells resist c-Jun induced differentiation when in suspension

The oncogene c-Jun plays a key role in development and cancer. Yet, its role in cell fate decision remains poorly understood at the molecular level. Here we report that c-Jun confers different fate decisions upon mouse embryonic stem cells (mESCs) in adhesion vs suspension culture. We developed a Te...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Dongwei, Chen, Jiekai, Liu, Jing, Pei, Duanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326245/
https://www.ncbi.nlm.nih.gov/pubmed/30671225
http://dx.doi.org/10.1016/j.cr.2018.05.002