A functional variant of SMAD4 enhances macrophage recruitment and inflammatory response via TGF-β signal activation in Thoracic aortic aneurysm and dissection

Thoracic aortic aneurysm and dissection (TAAD) is the most fatal macro vascular disease. The mortality of 48h after diagnosis of dissection is up to approximately 50-68%. However, the genetic factors and potential mechanism underlying sporadic TAAD remain largely unknown. Our previous study suggeste...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Yin, Pei, Chen, Yi-Huan, Yu, Yun-Sheng, Ye, Wen-Xue, Huang, Hao-Yue, Ji, Zhen-Chun, Shen, Zhen-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326647/
https://www.ncbi.nlm.nih.gov/pubmed/30530919
http://dx.doi.org/10.18632/aging.101662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326647/
https://www.ncbi.nlm.nih.gov/pubmed/30530919
http://dx.doi.org/10.18632/aging.101662

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