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SNCA overexpression disturbs hippocampal gene expression trajectories in midlife

Synucleinopathies like Parkinson’s disease and dementia with Lewy bodies originate from a complex and still largely enigmatic interplay of genetic predisposition, age, and environmental factors. While progressively declining motor functions hallmark late-life symptoms, first signs of the disease oft...

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Detalles Bibliográficos
Autores principales: Hentrich, Thomas, Wassouf, Zinah, Riess, Olaf, Schulze-Hentrich, Julia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326667/
https://www.ncbi.nlm.nih.gov/pubmed/30543522
http://dx.doi.org/10.18632/aging.101691