Autophagy delays progression of the two most frequent human monogenetic lethal diseases: cystic fibrosis and Wilson disease

Cystic fibrosis (CF) and Wilson disease (WD) are two monogenetic, recessively inherited lethal pathologies that are caused by ionic disequilibria. CF results from loss-of-function mutations in CF transmembrane conductance regulator (CFTR), a channel that conducts chloride across epithelial cell memb...

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Detalles Bibliográficos
Autores principales: Maiuri, Luigi, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326686/
https://www.ncbi.nlm.nih.gov/pubmed/30568028
http://dx.doi.org/10.18632/aging.101736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326686/
https://www.ncbi.nlm.nih.gov/pubmed/30568028
http://dx.doi.org/10.18632/aging.101736

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