Structure and function of an ectopic Polycomb chromatin domain

Polycomb group proteins (PcGs) drive target gene repression and form large chromatin domains. In Drosophila, DNA elements known as Polycomb group response elements (PREs) recruit PcGs to the DNA. We have shown that, within the invected-engrailed (inv-en) Polycomb domain, strong, constitutive PREs ar...

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Detalles Bibliográficos
Autores principales: De, Sandip, Cheng, Yuzhong, Sun, Ming-an, Gehred, Natalie D., Kassis, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326746/
https://www.ncbi.nlm.nih.gov/pubmed/30662949
http://dx.doi.org/10.1126/sciadv.aau9739