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Inversion of a large-scale circuit model reveals a cortical hierarchy in the dynamic resting human brain

We considered a large-scale dynamical circuit model of human cerebral cortex with region-specific microscale properties. The model was inverted using a stochastic optimization approach, yielding markedly better fit to new, out-of-sample resting functional magnetic resonance imaging (fMRI) data. With...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Kong, Ru, Kong, Xiaolu, Liégeois, Raphaël, Orban, Csaba, Deco, Gustavo, van den Heuvel, Martijn P., Thomas Yeo, B.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326747/
https://www.ncbi.nlm.nih.gov/pubmed/30662942
http://dx.doi.org/10.1126/sciadv.aat7854