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Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection

In retinal detachment (RD), photoreceptor death and permanent vision loss are caused by neurosensory retina separating from the retinal pigment epithelium because of subretinal fluid (SRF), and successful surgical reattachment is not predictive of total visual recovery. As retinal iron overload exac...

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Detalles Bibliográficos
Autores principales: Daruich, Alejandra, Le Rouzic, Quentin, Jonet, Laurent, Naud, Marie-Christine, Kowalczuk, Laura, Pournaras, Jean-Antoine, Boatright, Jeffrey H., Thomas, Aurélien, Turck, Natacha, Moulin, Alexandre, Behar-Cohen, Francine, Picard, Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326753/
https://www.ncbi.nlm.nih.gov/pubmed/30662950
http://dx.doi.org/10.1126/sciadv.aau9940