CRISPR-Cap: multiplexed double-stranded DNA enrichment based on the CRISPR system

Existing methods to enrich target regions of genomic DNA based on PCR, hybridization capture, or molecular inversion probes have various drawbacks, including long experiment times and low throughput and/or enrichment quality. We developed CRISPR-Cap, a simple and scalable CRISPR-based method to enri...

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Detalles Bibliográficos
Autores principales: Lee, Jeewon, Lim, Hyeonseob, Jang, Hoon, Hwang, Byungjin, Lee, Joon Ho, Cho, Junhyuk, Lee, Ji Hyun, Bang, Duhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326800/
https://www.ncbi.nlm.nih.gov/pubmed/30215766
http://dx.doi.org/10.1093/nar/gky820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326800/
https://www.ncbi.nlm.nih.gov/pubmed/30215766
http://dx.doi.org/10.1093/nar/gky820

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