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CRISPR-Cap: multiplexed double-stranded DNA enrichment based on the CRISPR system
Existing methods to enrich target regions of genomic DNA based on PCR, hybridization capture, or molecular inversion probes have various drawbacks, including long experiment times and low throughput and/or enrichment quality. We developed CRISPR-Cap, a simple and scalable CRISPR-based method to enri...
Autores principales: | Lee, Jeewon, Lim, Hyeonseob, Jang, Hoon, Hwang, Byungjin, Lee, Joon Ho, Cho, Junhyuk, Lee, Ji Hyun, Bang, Duhee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326800/ https://www.ncbi.nlm.nih.gov/pubmed/30215766 http://dx.doi.org/10.1093/nar/gky820 |
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