DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex

Cortical development is controlled by transcriptional programs, which are orchestrated by transcription factors. Yet, stable inheritance of spatio-temporal activity of factors influencing cell fate and localization in different layers is only partly understood. Here we find that deletion of Dot1l in...

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Detalles Bibliográficos
Autores principales: Franz, Henriette, Villarreal, Alejandro, Heidrich, Stefanie, Videm, Pavankumar, Kilpert, Fabian, Mestres, Ivan, Calegari, Federico, Backofen, Rolf, Manke, Thomas, Vogel, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326801/
https://www.ncbi.nlm.nih.gov/pubmed/30329130
http://dx.doi.org/10.1093/nar/gky953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326801/
https://www.ncbi.nlm.nih.gov/pubmed/30329130
http://dx.doi.org/10.1093/nar/gky953

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