Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI

BbvCI, a Type IIT restriction endonuclease, recognizes and cleaves the seven base pair sequence 5′-CCTCAGC-3′, generating 3-base, 5′-overhangs. BbvCI is composed of two protein subunits, each containing one catalytic site. Either site can be inactivated by mutation resulting in enzyme variants that...

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Detalles Bibliográficos
Autores principales: Shen, Betty W, Doyle, Lindsey, Bradley, Phil, Heiter, Daniel F, Lunnen, Keith D, Wilson, Geoffrey G, Stoddard, Barry L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326814/
https://www.ncbi.nlm.nih.gov/pubmed/30395313
http://dx.doi.org/10.1093/nar/gky1059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326814/
https://www.ncbi.nlm.nih.gov/pubmed/30395313
http://dx.doi.org/10.1093/nar/gky1059

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