Resting cells rely on the DNA helicase component MCM2 to build cilia

Minichromosome maintenance (MCM) proteins facilitate replication by licensing origins and unwinding the DNA double strand. Interestingly, the number of MCM hexamers greatly exceeds the number of firing origins suggesting additional roles of MCMs. Here we show a hitherto unanticipated function of MCM...

Descripción completa

Detalles Bibliográficos
Autores principales: Casar Tena, Teresa, Maerz, Lars D, Szafranski, Karol, Groth, Marco, Blätte, Tamara J, Donow, Cornelia, Matysik, Sabrina, Walther, Paul, Jeggo, Penelope A, Burkhalter, Martin D, Philipp, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326816/
https://www.ncbi.nlm.nih.gov/pubmed/30329080
http://dx.doi.org/10.1093/nar/gky945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326816/
https://www.ncbi.nlm.nih.gov/pubmed/30329080
http://dx.doi.org/10.1093/nar/gky945

Ejemplares similares