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Structure guided fluorescence labeling reveals a two-step binding mechanism of neomycin to its RNA aptamer
The ability of the cytidine analog Ç(m)(f) to act as a position specific reporter of RNA-dynamics was spectroscopically evaluated. Ç(m)(f)-labeled single- and double-stranded RNAs differ in their fluorescence lifetimes, quantum yields and anisotropies. These observables were also influenced by the n...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326822/ https://www.ncbi.nlm.nih.gov/pubmed/30462266 http://dx.doi.org/10.1093/nar/gky1110 |