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Design of highly active double-pseudoknotted ribozymes: a combined computational and experimental study
Design of RNA sequences that adopt functional folds establishes principles of RNA folding and applications in biotechnology. Inverse folding for RNAs, which allows computational design of sequences that adopt specific structures, can be utilized for unveiling RNA functions and developing genetic too...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326823/ https://www.ncbi.nlm.nih.gov/pubmed/30462314 http://dx.doi.org/10.1093/nar/gky1118 |