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Design of highly active double-pseudoknotted ribozymes: a combined computational and experimental study

Design of RNA sequences that adopt functional folds establishes principles of RNA folding and applications in biotechnology. Inverse folding for RNAs, which allows computational design of sequences that adopt specific structures, can be utilized for unveiling RNA functions and developing genetic too...

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Detalles Bibliográficos
Autores principales: Yamagami, Ryota, Kayedkhordeh, Mohammad, Mathews, David H, Bevilacqua, Philip C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326823/
https://www.ncbi.nlm.nih.gov/pubmed/30462314
http://dx.doi.org/10.1093/nar/gky1118