Cargando…
Design of highly active double-pseudoknotted ribozymes: a combined computational and experimental study
Design of RNA sequences that adopt functional folds establishes principles of RNA folding and applications in biotechnology. Inverse folding for RNAs, which allows computational design of sequences that adopt specific structures, can be utilized for unveiling RNA functions and developing genetic too...
Autores principales: | Yamagami, Ryota, Kayedkhordeh, Mohammad, Mathews, David H, Bevilacqua, Philip C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326823/ https://www.ncbi.nlm.nih.gov/pubmed/30462314 http://dx.doi.org/10.1093/nar/gky1118 |
Ejemplares similares
-
RNA pseudoknots
por: Westhof, Eric, et al.
Publicado: (1992) -
The NTP binding site of the polymerase ribozyme
por: Akoopie, Arvin, et al.
Publicado: (2018) -
A ribozyme that uses lanthanides as cofactor
por: Sweeney, Kevin J, et al.
Publicado: (2023) -
Systematic minimization of RNA ligase ribozyme through large-scale design-synthesis-sequence cycles
por: Nomura, Yoko, et al.
Publicado: (2019) -
Small synthetic molecule-stabilized RNA pseudoknot as an activator for –1 ribosomal frameshifting
por: Matsumoto, Saki, et al.
Publicado: (2018)