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Identification of molecular signatures involved in radiation-induced lung fibrosis

ABSTRACT: In radiotherapy, radiation (IR)-induced lung fibrosis has severe and dose-limiting side effects. To elucidate the molecular effects of IR fibrosis, we examined the fibrosis process in irradiated mouse lung tissues. High focal IR (90 Gy) was exposed to a 3-mm volume of the left lung in C57B...

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Detalles Bibliográficos
Autores principales: Jin, Hee, Kang, Ga-Young, Jeon, Seulgi, Kim, Jin-Mo, Park, You Na, Cho, Jaeho, Lee, Yun-Sil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326977/
https://www.ncbi.nlm.nih.gov/pubmed/30406363
http://dx.doi.org/10.1007/s00109-018-1715-9