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Non-Invasive Multimodality Imaging Directly Shows TRPM4 Inhibition Ameliorates Stroke Reperfusion Injury

The transient receptor potential melastatin 4 (TRPM4) channel has been suggested to play a key role in the treatment of ischemic stroke. However, in vivo evaluation of TRPM4 channel, in particular by direct channel suppression, is lacking. In this study, we used multimodal imaging to assess edema fo...

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Detalles Bibliográficos
Autores principales: Chen, Bo, Ng, Gandi, Gao, Yahui, Low, See Wee, Sandanaraj, Edwin, Ramasamy, Boominathan, Sekar, Sakthivel, Bhakoo, Kishore, Soong, Tuck Wah, Nilius, Bernd, Tang, Carol, Robins, Edward G., Goggi, Julian, Liao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327008/
https://www.ncbi.nlm.nih.gov/pubmed/29569041
http://dx.doi.org/10.1007/s12975-018-0621-3