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Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche

In many tissues, homeostasis is maintained by physical contact between stem cells and an anatomically defined niche. However, how stem cell homeostasis is achieved in environments where cells are motile and dispersed among their progeny remains unknown. Using murine spermatogenesis as a model, we fi...

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Detalles Bibliográficos
Autores principales: Kitadate, Yu, Jörg, David J., Tokue, Moe, Maruyama, Ayumi, Ichikawa, Rie, Tsuchiya, Soken, Segi-Nishida, Eri, Nakagawa, Toshinori, Uchida, Aya, Kimura-Yoshida, Chiharu, Mizuno, Seiya, Sugiyama, Fumihiro, Azami, Takuya, Ema, Masatsugu, Noda, Chiyo, Kobayashi, Satoru, Matsuo, Isao, Kanai, Yoshiakira, Nagasawa, Takashi, Sugimoto, Yukihiko, Takahashi, Satoru, Simons, Benjamin D., Yoshida, Shosei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327111/
https://www.ncbi.nlm.nih.gov/pubmed/30581080
http://dx.doi.org/10.1016/j.stem.2018.11.013