Detection of endoplasmic reticulum stress and the unfolded protein response in naturally-occurring endocrinopathic equine laminitis

BACKGROUND: Laminitis is often associated with endocrinopathies that cause hyperinsulinemia and is also induced experimentally by hyperinsulinemia, suggesting that insulin initiates laminitis pathogenesis. Hyperinsulinemia is expected to activate pro-growth and anabolic signaling pathways. We hypoth...

Descripción completa

Detalles Bibliográficos
Autores principales: Cassimeris, Lynne, Engiles, Julie B., Galantino-Homer, Hannah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327420/
https://www.ncbi.nlm.nih.gov/pubmed/30630474
http://dx.doi.org/10.1186/s12917-018-1748-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327420/
https://www.ncbi.nlm.nih.gov/pubmed/30630474
http://dx.doi.org/10.1186/s12917-018-1748-x

Ejemplares similares