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Detection of endoplasmic reticulum stress and the unfolded protein response in naturally-occurring endocrinopathic equine laminitis

BACKGROUND: Laminitis is often associated with endocrinopathies that cause hyperinsulinemia and is also induced experimentally by hyperinsulinemia, suggesting that insulin initiates laminitis pathogenesis. Hyperinsulinemia is expected to activate pro-growth and anabolic signaling pathways. We hypoth...

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Detalles Bibliográficos
Autores principales:	Cassimeris, Lynne, Engiles, Julie B., Galantino-Homer, Hannah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327420/ https://www.ncbi.nlm.nih.gov/pubmed/30630474 http://dx.doi.org/10.1186/s12917-018-1748-x

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