Cargando…

Modified enzyme multiplied immunoassay technique of methotrexate assay to improve sensitivity and reduce cost

BACKGROUND: Methotrexate is an important component in many chemotherapy protocols. The blood concentration of Methotrexate is used to determine the regimen of folinic acid. However, the lower limit of Siemens assay kit is 0.30 μmol/L in China. This study extended the limit from 0.3 to 0.05 μmol/L an...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Xiaoping, Gao, Hui, Li, Zhong, Li, Jinghua, Liu, Yang, Li, Lujuan, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327437/
https://www.ncbi.nlm.nih.gov/pubmed/30626430
http://dx.doi.org/10.1186/s40360-018-0283-5