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Modified enzyme multiplied immunoassay technique of methotrexate assay to improve sensitivity and reduce cost
BACKGROUND: Methotrexate is an important component in many chemotherapy protocols. The blood concentration of Methotrexate is used to determine the regimen of folinic acid. However, the lower limit of Siemens assay kit is 0.30 μmol/L in China. This study extended the limit from 0.3 to 0.05 μmol/L an...
Autores principales: | Shi, Xiaoping, Gao, Hui, Li, Zhong, Li, Jinghua, Liu, Yang, Li, Lujuan, Zhang, Qi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327437/ https://www.ncbi.nlm.nih.gov/pubmed/30626430 http://dx.doi.org/10.1186/s40360-018-0283-5 |
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