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Phenotypic plasticity and the evolution of azole resistance in Aspergillus fumigatus; an expression profile of clinical isolates upon exposure to itraconazole

BACKGROUND: The prevalence of azole resistance in clinical and environmental Aspergillus fumigatus isolates is rising over the past decades, but the molecular basis of the development of antifungal drug resistance is not well understood. This study focuses on the role of phenotypic plasticity in the...

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Detalles Bibliográficos
Autores principales: Hokken, Margriet W. J., Zoll, Jan, Coolen, Jordy P. M., Zwaan, Bas J., Verweij, Paul E., Melchers, Willem J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327609/
https://www.ncbi.nlm.nih.gov/pubmed/30626317
http://dx.doi.org/10.1186/s12864-018-5255-z