Synthesis of a novel p-hydroxycinnamic amide with anticancer capability and its interaction with human serum albumin

In the present study, a novel p-hydroxycinnamic amide (E)-3-(4-hydroxyphenyl)-N-(4-(N-(5-meth oxypyrimidin-2-yl)-sulfamoyl)phenyl)acrylamide (HMSP) was synthesized and confirmed. In vitro cytotoxic assays indicated that HMSP was able to inhibit the proliferation of various cancer cell lines. The int...

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Detalles Bibliográficos
Autores principales: Jiao, Yuan-Hong, Meng, Fa-Yan, Zhu, Gui-Bing, Ran, Ling-Zi, Jiang, Yu-Feng, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327636/
https://www.ncbi.nlm.nih.gov/pubmed/30680009
http://dx.doi.org/10.3892/etm.2018.7060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327636/
https://www.ncbi.nlm.nih.gov/pubmed/30680009
http://dx.doi.org/10.3892/etm.2018.7060

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