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Recurring and Adaptable Binding Motifs in Broadly Neutralizing Antibodies to Influenza Virus Are Encoded on the D3-9 Segment of the Ig Gene

Discovery and characterization of broadly neutralizing antibodies (bnAbs) to the influenza hemagglutinin (HA) stem have provided insights for the development of a universal flu vaccine. Identification of signature features common to bnAbs from different individuals will be key to guiding immunogen d...

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Detalles Bibliográficos
Autores principales: Wu, Nicholas C., Yamayoshi, Seiya, Ito, Mutsumi, Uraki, Ryuta, Kawaoka, Yoshihiro, Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327842/
https://www.ncbi.nlm.nih.gov/pubmed/30308159
http://dx.doi.org/10.1016/j.chom.2018.09.010