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Recurring and Adaptable Binding Motifs in Broadly Neutralizing Antibodies to Influenza Virus Are Encoded on the D3-9 Segment of the Ig Gene
Discovery and characterization of broadly neutralizing antibodies (bnAbs) to the influenza hemagglutinin (HA) stem have provided insights for the development of a universal flu vaccine. Identification of signature features common to bnAbs from different individuals will be key to guiding immunogen d...
Autores principales: | Wu, Nicholas C., Yamayoshi, Seiya, Ito, Mutsumi, Uraki, Ryuta, Kawaoka, Yoshihiro, Wilson, Ian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327842/ https://www.ncbi.nlm.nih.gov/pubmed/30308159 http://dx.doi.org/10.1016/j.chom.2018.09.010 |
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