Cargando…

EphA4-ADAM10 Interplay Patterns the Cochlear Sensory Epithelium through Local Disruption of Adherens Junctions

The cochlear sensory epithelium contains a functionally important triangular fluid-filled space between adjacent pillar cells referred to as the tunnel of Corti. However, the molecular mechanisms leading to local cell-cell separation during development remain elusive. Here we show that EphA4 associa...

Descripción completa

Detalles Bibliográficos
Autores principales: Defourny, Jean, Peuckert, Christiane, Kullander, Klas, Malgrange, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327856/
https://www.ncbi.nlm.nih.gov/pubmed/30639848
http://dx.doi.org/10.1016/j.isci.2018.12.017