Inhibition of MEK1/2 and GSK3 (2i system) affects blastocyst quality and early differentiation of porcine parthenotes

Inhibition of both MEK1/2 and glycogen synthase kinase-3 (GSK3; 2i system) facilitates the maintenance of naïve stemness for embryonic stem cells in various mammalian species. However, the effect of the inhibition of the 2i system on porcine early embryogenesis is unknown. We investigated the effect...

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Detalles Bibliográficos
Autores principales: Kwon, Jeongwoo, Li, Ying-Hua, Jo, Yu-Jin, Oh, YoungJin, Namgoong, Suk, Kim, Nam-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327883/
https://www.ncbi.nlm.nih.gov/pubmed/30643672
http://dx.doi.org/10.7717/peerj.5840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327883/
https://www.ncbi.nlm.nih.gov/pubmed/30643672
http://dx.doi.org/10.7717/peerj.5840

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