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The impact of camptothecin-encapsulated poly(lactic-co-glycolic acid) nanoparticles on the activity of cytochrome P450 in vitro

BACKGROUND: Poly(lactic-co-glycolic acid) (PLGA) has emerged as a promising anticancer drug delivery scaffold. Camptothecin (CPT) has been fabricated into a variety of nanosized formulations to improve drug action. We report an experimental study on the effect of CPT-encapsulated PLGA (PLGA-CPT) nan...

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Detalles Bibliográficos
Autores principales: Bao, Hanmei, Zhang, Qing, Yan, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327902/
https://www.ncbi.nlm.nih.gov/pubmed/30662262
http://dx.doi.org/10.2147/IJN.S188984