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Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches

The aim of the present study was to define the role of Trx and Grx on metabolic thiol redox regulation and identify their protein and metabolite targets. The hepatocarcinoma-derived HepG2 cell line under both normal and oxidative/nitrosative conditions by overexpression of NO synthase (NOS3) was use...

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Detalles Bibliográficos
Autores principales: López-Grueso, MJ, González-Ojeda, R, Requejo-Aguilar, R, McDonagh, B, Fuentes-Almagro, CA, Muntané, J., Bárcena, J.A., Padilla, CA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327914/
https://www.ncbi.nlm.nih.gov/pubmed/30639960
http://dx.doi.org/10.1016/j.redox.2018.11.007