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Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches
The aim of the present study was to define the role of Trx and Grx on metabolic thiol redox regulation and identify their protein and metabolite targets. The hepatocarcinoma-derived HepG2 cell line under both normal and oxidative/nitrosative conditions by overexpression of NO synthase (NOS3) was use...
Autores principales: | López-Grueso, MJ, González-Ojeda, R, Requejo-Aguilar, R, McDonagh, B, Fuentes-Almagro, CA, Muntané, J., Bárcena, J.A., Padilla, CA |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327914/ https://www.ncbi.nlm.nih.gov/pubmed/30639960 http://dx.doi.org/10.1016/j.redox.2018.11.007 |
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