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Recombinant asialoerythropoetin protects HL-1 cardiomyocytes from injury via suppression of Mst1 activation

BACKGROUND: Recombinant human erythropoietin (rhuEPO) and asialoerythropoietin (asialo-rhuEPO) are cardioprotective. However, the protective effects of rhuEPO could not be translated into clinical practice because of its hematopoiesis-associated side effects while non-erythropoietic asialo-rhuEPO is...

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Detalles Bibliográficos
Autores principales: Kittur, Farooqahmed S., Lin, Yuan, Arthur, Elena, Hung, Chiu-Yueh, Li, P. Andy, Sane, David C., Xie, Jiahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327940/
https://www.ncbi.nlm.nih.gov/pubmed/30671548
http://dx.doi.org/10.1016/j.bbrep.2019.01.004