Organoruthenium(II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII

Two acetazolamide (AAZ) complexes with ruthenium(II) η(6)-p-cymene chloride were synthesised, characterised and tested for their inhibitory effects on several carbonic anhydrase (CA, EC 4.2.1.1) isoforms with pharmacological applications. Against human (h) isoform hCA I, the two complexes showed inh...

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Detalles Bibliográficos
Autores principales: Seršen, Sara, Traven, Katja, Kljun, Jakob, Turel, Iztok, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327979/
https://www.ncbi.nlm.nih.gov/pubmed/30734595
http://dx.doi.org/10.1080/14756366.2018.1547288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327979/
https://www.ncbi.nlm.nih.gov/pubmed/30734595
http://dx.doi.org/10.1080/14756366.2018.1547288

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