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New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases

A series of organometallic acylhydrazones was prepared, incorporating Re(CO)(3), Mn(CO)(3) and ferrocenyl moieties, which were subsequently reacted with amino-sulfonamides in order to obtain carbonic anhydrase (CA, EC 4.2.1.1) inhibitors possessing organometallic moieties in their molecules. The new...

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Detalles Bibliográficos
Autores principales: Huentupil, Yosselin, Peña, Luis, Novoa, Néstor, Berrino, Emanuela, Arancibia, Rodrigo, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327986/
https://www.ncbi.nlm.nih.gov/pubmed/30734605
http://dx.doi.org/10.1080/14756366.2018.1555156